February 18 2005 Construction at Arcosanti curren

first_imgFebruary 18, 2005Construction at Arcosanti currently focusses on installing utilities for the East Crescent complex. This phase of the Arcosanti project includes a new classroom, meeting room and a number of residential units. The construction crew consists of February 6.Construction at Arcosanti currently focusses on installing utilities for the East Crescent complex. This phase of the Arcosanti project includes a new classroom, meeting room and a number of residential units. The construction crew consists of February 6. workshop participants, Arcosanti crew leaders and volunteers.   From the heat duct tunnel underneath the building, construction volunteer Mika Kawai and local contractor Sean Wright pull electrical wiring through the walls. [Photo: Yuki Yanagimoto & text: Jacob Schwartz] The community library is located in one of the first floor rooms of the East Crescent. From here, crew leader Michael Bittman and workshop participants April Braly and Kelley McLaughlin feed the wires. More on this on 2/21. [Photo: Scott W Riley & text: Jacob Schwartz]last_img read more

Nordic subscription videoondemand service Viapla

first_imgNordic subscription video-on-demand service Viaplay saw viewing time increase by 25% during 2017, according to stats released by parent company MTG.Alexander BastinCustomers spent an average of 32 hours per month streaming Viaplay last year, while the number of started streams rose 40.5% between 2016 and 2017.Over the same period, MTG said the total number of Viaplay customers grew by 21%, with Viaplay original productions among most viewed new series in each Nordic country in 2017.Among Viaplay’s original output, Hassel was the service’s most-watched new series in Sweden and Finland; Veni Vidi Vici was the second most-watched new-series in Demark; and Occupied season two was the second most-watched new series in Norway.Overall eight Viaplay original productions premiered during 2017. MTG said that Viaplay also streamed 50,000 hours of live sport in 2017, including Premier League and UEFA Champions League football.In terms of viewing habits, MTG said that viewing on TVs or projectors surpassed mobile devices for the first time since Viaplay launched in 2011, with a user base of 64% compared to 61% for mobile as of December 2017.“More than one hour every day tells its own story – Viaplay is truly creating moments that matter,” said Anders Jensen, MTG executive vice-president and chairman of Nordic Entertainment.“In just a few years, we’ve become a Nordic drama powerhouse producing amazing original content that’s captivating audiences across the region and beyond. On big screens and small, our stories have never been more relevant.”Alexander Bastin, head of Viaplay, said: “Viaplay is rapidly attracting more customers, and they are watching more than ever before. In parallel, the app for Viafree, our free streaming service in the Nordic region, has been downloaded close to 2.6 million times. It just shows what’s possible when fantastic stories meet the most advanced and accessible platforms in the business.”The news comes shortly after MTG’s plan to sell MTG Studios and Nordic Entertainment – divisions that include Viaplay, Viafree and its entire production output – fell through.MTG announced earlier this month that it had agreed to sell its Nordic broadcasting and entertainment businesses to Danish telco TDC in a deal that valued the assets at SEK19.55 billion (€2.0 billion).However, TDC pulled out of the deal after it accepted a €5.4 billion takeover offer from a consortium of bidders. The offer was contingent on the MTG-TDC deal not proceeding.last_img read more

Soyasapogenol B A new drug delivery technology for therapeutics

first_imgReviewed by James Ives, M.Psych. (Editor)Dec 24 2018Multi-Walled Carbon Nanotubes (MWCNTs) are characterized by walls formed by a one atom thick sheet of carbon. Using MWCNTs as a drug delivery system, the requirement for the solvent and drug dissolution in a solution can be avoided. Soyasapogenol B (SSB) is a product derived from soya bean that belongs to the family of oleanane triterpenes. It is also known to have biological functions in cell signaling, membrane integrity and stability and energy storage. Soyasapogenol B may demonstrate hypo-cholesterolemic effects. Soyasapogenol B happens to be an important therapeutic agent due to its many biological activities. SSB can be loaded with MWCNTs with tetraethyl orthosilicate (TEOS) and/or chitosan.Related StoriesNew study reveals ‘clutch’ proteins responsible for putting T cell activation ‘into gear’Olympus Europe and Cytosurge join hands to accelerate drug development, single cell researchScreenIn3D receives technology innovation prizeBy using miniemulsion techniques, SBB was immobilized onto MWCNTs. Additionally, niosomes were used to enclose the prepared systems. The analysis of the particle systems was done by Fourier Transform Infrared Spectroscopy (FTIS), Transmission Electron Microscopy (TEM), and size distribution analysis. Kinematics of the release of the particles and SBB particles that had an in vitro release profiles, were carried out. In vitro cytotoxicity of synthesized materials was analyzed and was examined by using cell lines such as normal melanocytes (HFB4), liver and carcinoma breast by the comparison with standard doxorubicin.The results of the experiment revealed that SSB loaded materials were able to display controlled and sustained drug release, which also obeyed mathematical in vitro profiles in line with multiple models. The preparations were also minimally cytotoxic in all cell lines tested.The research demonstrates the use of loading a bioactive agent such as SSB into MWCNTs to deliver it into multiple cell types with minimal toxicity. This is useful information for reasearchers looking into new drug delivery technologies for therapeutics.Source: https://benthamscience.com/last_img read more

Mothers treatment for infection during pregnancy increases childs risk for autism and

first_imgReviewed by James Ives, M.Psych. (Editor)Mar 8 2019Risks for autism and depression are higher if one’s mother was in hospital with an infection during pregnancy. This is shown by a major Swedish observational study of nearly 1.8 million children.”The results indicate that safeguarding against and preventing infection during pregnancy as far as possible by, for instance, following flu vaccination recommendations, may be called for,” says Verena Sengpiel, Associate Professor of Obstetrics and Gynecology at Sahlgrenska Academy, University of Gothenburg, and last author of the study, published in the journal JAMA Psychiatry.Maternal infection with certain infectious agents, such as cytomegalovirus (CMV) or the herpes virus, are already known to be capable of harming fetal brain development and boosting the risk of certain psychiatric disorders.The findings of the current study, however, also show that infection in general during pregnancy, too — including when the actual infectious agent does not reach the fetal brain — is related to elevated risk of the child developing autism or depression later in life.More autism and depressionThe study is based on data on all children, totaling almost 1.8 million, born in Sweden during the years 1973-2014. The particulars from the Swedish Medical Birth Register were linked to the national inpatient register, which records whether the mother was treated in hospital with an infection diagnosis during the pregnancy concerned.Using the inpatient register, the researchers also monitored these children’s mental health until 2014, when the oldest were aged 41.It was found that if, during pregnancy, a mother with an infection diagnosis received hospital treatment, there was a marked rise in the risk of her child needing hospital care later in life, with a diagnosis of either autism or depression. The increase in risk was 79 percent for autism and 24 percent for depression.Related StoriesStudy uncovers potential new way to prevent common pregnancy-related complicationsWomen’s pre-pregnancy obesity changes breast milk contents which can affect infant growthPregnant women with migraine more often have complications during pregnancy and childbirthIn contrast, there was no association between the mothers being in hospital with an infection diagnosis during pregnancy and two other psychiatric diagnoses studied in their children: bipolar disorder and psychosis, including schizophrenia.Increased risk even after mild infectionThe pregnant women in the study may have been hospitalized with diagnoses other than infections, but then had infections diagnosed during their stay as well. The elevated risk of mental ill-health in the child was also evident after infections in the pregnant women that are usually considered mild, such as a common urinary tract infection.The study, which was observational, provides no answer on how maternal infection during pregnancy affects fetal brain development. However, other studies have shown that an infection in the mother leads to an inflammatory reaction, and that some inflammatory proteins can affect gene expression in fetal brain cells.Other research shows that inflammation in the mother boosts production of the neurotransmitter serotonin in the placenta, which may conceivably affect the unborn child’s brain development.https://www.gu.se/english/about_the_university/news-calendar/News_detail//child-s-elevated-mental-ill-health-risk-if-mother-treated-for-infection-during-pregnancy.cid1619697last_img read more

Women experiencing minor stroke are less likely to be diagnosed than men

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)May 23 2019Women experiencing a minor stroke or transient ischemic attack (TIA) are less likely to be diagnosed with a stroke compared to men — even though they describe similar symptoms in emergency departments. The findings of the study are published in JAMA Neurology and were presented May 22 at the European Stroke Organisation Conference in Milan, Italy.The study found men and women equally described atypical stroke symptoms such as dizziness, tingling or confusion which are not commonly thought of as related to stroke. Typical symptoms of stroke are sudden weakness, face drooping, or speech difficulties.A TIA occurs when there is temporary interruption of blood flow to the brain, and is often a warning sign of another stroke. TIAs can also be associated with permanent disability.Discrepancy in diagnoses”Our study also found the chance of having another stroke or heart attack within 90 days of the diagnosis was the same for women and men,” adds senior author Dr. Shelagh Coutts, MD, a stroke neurologist with Alberta Health Services at Foothills Medical Centre, associate professor at the University of Calgary’s Cumming School of Medicine (CSM) and member of the Hotchkiss Brain Institute at the CSM.Researchers say while further research is needed, it is possible that patient reporting of symptoms, interpretation of symptoms by clinicians, or a combination of both, could explain the discrepancy in diagnosis among men and women.”Our findings call attention to potential missed opportunities for prevention of stroke and other adverse vascular events such as heart attack or death in women,” adds Coutts.Previous studies on this topic have focused on patients diagnosed with stroke. Researchers in the current study included 1,648 patients with suspected TIA who were referred to a neurologist after receiving emergency care from 2013-2017, regardless of their final diagnosis.Spotlight on atypical symptomsRelated StoriesPeople who worked long hours have higher risk of stroke, shows studyInvestment in stroke prevention interventions is good for the futureNew approach to post-stroke rehabilitation proposedResearchers note it is an important opportunity for the public and clinicians to be aware of atypical symptoms of TIA.”What’s important to recognize in stroke is that the brain has so many different functions and when a stroke is happening, people can feel different things beyond the typical stroke symptoms,” says Yu. “Accurately diagnosing TIA and stroke would change a patient’s treatment plan and could help prevent another stroke from happening.”Funding for the study was provided by Genome Canada, Genome B.C., Genome Alberta, and the Heart and Stroke Foundation of Canada.Dr. Amy Yu, MD, is an assistant professor at the University of Toronto, an associate scientist at the Sunnybrook Research Institute, and stroke neurologist at the Sunnybrook Health Sciences Centre.Dr. Shelagh Coutts, MD, is an associate professor in the departments of Clinical Neurosciences, Radiology, and Community Health Sciences and a member of the Hotchkiss Brain Institute at the Cumming School of Medicine, University of Calgary.Led by the Hotchkiss Brain Institute, Brain and Mental Health is one of six research strategies guiding the University of Calgary toward its Eyes High goals. The strategy provides a unifying direction for brain and mental health research at the university and positions researchers to unlock new discoveries and treatments for brain health in our community.Source:University of CalgaryJournal reference:Yu, A. et al. (2019) Sex Differences in Presentation and Outcome After an Acute Transient or Minor Neurologic Event. JAMA Neurology. doi.org/10.1001/jamaneurol.2019.1305. In our study, men were more likely to be diagnosed with TIA or minor stroke, and women were 10 per cent more likely to be given a non-stroke diagnosis, for example migraine or vertigo, even though men and women were equally likely to report atypical stroke symptoms.”Dr. Amy Yu, MD, stroke neurologist at Sunnybrook Health Sciences Centre and assistant professor at the University of Toronto, study lead authorlast_img read more

Financial incentives may help people quit smoking and remain smokefree

first_img“We wanted to know whether these schemes actually work long term, as previously it was thought that perhaps incentives only worked for the time that they were given. We found that they do help people stay smoke free, even after the incentive scheme ends. Smoking is the leading cause of disease and death worldwide. Most smokers want to quit, but stopping smoking can be really challenging.Quitting smoking can greatly improve peoples’ health. Rewards, such as money or vouchers, have been used to encourage smokers to quit, and to reward them if they stay stopped. Such schemes have been used in workplaces, in clinics and hospitals, and within community programs.” Reviewed by James Ives, M.Psych. (Editor)Jul 17 2019Financial incentives work to help people stop smoking and remain smoke free – according to research led by the University of East Anglia (UEA).Evidence published today in the Cochrane Library provides strong evidence that financial incentives helped people to stop smoking, and stay stopped long term.The review also found that incentives helped pregnant women stop smoking.Lead author Dr Caitlin Notley, from UEA’s Norwich Medical School:center_img “The cost of smoking to the economy is huge – around £13 billion to the UK economy, including over £3 billion for NHS and social care and £7.5 billion to lost productivity. So these types of schemes could help save money as well as lives.”The team investigated whether rewards such as cash payments, vouchers, or the return of money deposited by those taking part, worked. The review summarizes the results from 33 randomized controlled trials involving more than 21,600 people from eight countries. They included ten trials that focused on pregnant smokers who were rewarded with vouchers for quitting and staying smoke-free.All of the trials in the general population followed participants for at least six months and those who quit were checked by testing their breath or bodily fluids.Some of the studies did not provide enough data for the team to fully assess their quality. But taking out the lowest quality trials from the analysis did not change the results.Related StoriesStudy: Less than 50% of U.S. adults exposed to court-ordered anti-smoking advertisementsStudy: Smoking does not shorten the length of telomeresEarly genome catastrophes can lead to development of lung cancer in non-smokersThe researchers say that the certainty of their findings in the general population is high. Their certainty about the findings in pregnant women is moderate, as there weren’t as many studies and some were lower quality.Dr Notley said: “We found that six months or more after the beginning of the trials, people receiving rewards were approximately 50 per cent more likely to have stopped smoking than those in the control groups.”In people not receiving incentives, approximately seven per cent had successfully quit for six months or longer, compared to approximately 10.5 per cent of those receiving incentives.”This is an important increase when we consider the enormous harms of smoking, and benefits of quitting, and suggests that incentives can be a useful part of a comprehensive approach to help people quit smoking. Another really important thing is that success rates continued beyond when the incentives had ended.”The total financial amount of incentives varied considerably between trials, from zero (self-deposits), to a range of between £35 ($45 USD) and £912 ($1185).Dr Notley added: “For pregnant women, we also found that women in the rewards groups were more likely to stop smoking than those in control groups – both at the end of the pregnancy and after the birth of the baby, suggesting incentives may be a useful part of a comprehensive approach to helping pregnant women quit smoking.”Stopping smoking during pregnancy is the best thing that women can do to improve their chances of having a healthy pregnancy. Staying stopped after the birth has great benefits for babies too, through avoiding exposure to second hand smoke.”The review was led by UEA, and involved researchers from the University of Oxford and the University of Stirling.’Incentives for smoking cessation’ is published by the Cochrane Library on July 17, 2019. Source:University of East Anglialast_img read more